Understanding Clinical Pharmacogenomics: A Descriptive Review

Pharmacogenomics in Clinical Practice

The Promise of Pharmacogenomics As genomic medicine advances, there is hope that genetic biomarkers will encourage movement away from empirical and population-based treatment approaches to those that are stratified according to better patient outcomes, thus ending a “trial-and-error” approach to therapy.4,6–8 It is estimated that only 50% of patients respond positively to their medications.5,9 ...

Pharmacokinetics and pharmacogenomics of tacrolimus: a review

Evaluation of Cultural Competency in Clinical Nurses: A Descriptive Study

Background & Aim: Cultural competence is the ability to work effectively as an individual or an organization in the context of the cultural beliefs, behaviors and needs of customers and society. Due to the necessity of this feature in nurses, the present study aimed to investigate the level of cultural competence in employed nurses. Methods: This descriptive study was performed on 230 nurses w...

Pharmacogenomics of glibenclamide in patients with type 2 diabetes mellitus: A systematic review

Introduction: One of the most widely used anti-diabetic drugs is sulfonylureas, which is often used as one of the first-line drugs in the treatment of type 2 diabetes. Due to the effect of the patient's genetic structure on the drug response (personalized medicine), the identification of genetic variations not only reduces the rate of adverse drug reactions but can also predict the effectivenes...

A Critical Review of Qualitative Articles in Journals’ Review Process: a Descriptive Exploratory Study

Introduction: Iranian researchers have increasingly been interested in conducting qualitative research studies in health system and publishing related articles. However, no research study was found to critically analyze qualitative articles in the review process of Iranian journals. The aim of this study has been to critically review qualitative articles in the review process of journals. Meth...